The website on humane endpointsHumane endpoint The moment in the experiment at which pain and/or distress experienced by the investigational animal is ended or alleviated by either killing the animal humanely or by discontinuing the procedure. has an ‘open’ and a ‘closed’ section.
The open section is accessible to everyone and contains general information on normal behaviour of mice and rats, by providing an overview of relevant laws and legislations, consisting of a database with relevant documents and publications and has a glossary of terms.

The closed section contains in-depth information about:

  • behaviour
  • clinical signs, both general and specific
  • assessment of painPain The negative sensory or emotional experience that indicates awareness in the animal of injury or the threat of injury to the body. This negative experience induces changes in an animal’s behavior and physiology, intended to limit the effect of, or avoid the injury, to reduce the chances of repeated injury and to promote recovery. and distressDistress It indicates a disadvantageous environment in which the animal is no longer able to adapt in a biologically successful manner to the stressors to which it is exposed. One speaks of distress when the level or the duration of stress are such that significant changes in biological function are required to survive.
  • pathology

And includes:

  • interactive training material
  • photo- and video of most clinical signs

This section is only accessible with a username and password. Access to this section can be requested by e-mail.

A password can be given to those who are:

  • affiliated to an institute performing biomedical research;
  • involved in biomedical research, testing and education (see ‘use for educational purposes’ below);
  • trained as an investigator, animal technician or another position which is closely linked to animal research, testing and education;
  • involved in relevant policy making activities, such as governmental organisations, regulatory bodies, etc.;
  • up to the decision of the project secretariat.

If you have a username and password: log in at the left side of the screen
If you don’t have a username and password: click here to register

Use for educational purposes

If you want to use this website for educational purposes and you need multiple login accounts, you can request students to register themselves by filling in the registration form here.

Students are allowed to keep using the humane endpoints website after course attendance, but can also delete their account.