Monitoring the welfareWelfare A complex and dynamic internal state that includes: successful biologic functioning, positive experiences, and absence of negative conditions. The animal adapts effectively to internal needs and external stimuli and maintains a good mental state. of each individual animal in the course of the experiment requires routine daily check-ups, adequate assessment of all aspects of animal welfare, and a reporting system. Of particular importance are the critical phases in the experiment during which the animal’s welfare may be at risk. Ideally, these critical phases should be identified at the start of the experiment. Conducting a pilot studyPilot study A small-scale experiment that is carried out in advance of the main investigation to test experimental methods and determine an animal’s responses, such as dose response, or adverse effects. Also called: pilot experiment / pilot test/ pilot. may be useful. Animals whose welfare can be expected to deteriorate, should be examined more frequently and more thoroughly.

Thorough assessment may include undisturbed observation, assessing the response to external stimuli and growth monitoring. Score sheetsScore sheet Form for recording clinical signs to determine animal well-being and if appropriate the application of a humane or scientific endpoint. can be used to record the findings.